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Over the next seven years, the network will conduct a series of studies to better understand influenza virus evolution, how influenza viruses jump from animals to humans, and how humans mount protective immune responses against these viruses. The CEIRR’s longitudinal studies will seek out how human responses to flu evolve over time.

Researchers will collect hundreds of samples from humans, pigs, and birds across the world each year. Investigators in the CEIRR network will conduct domestic and international influenza surveillance studies with an emphasis on rapid characterization of viruses that have the potential to cause pandemics. All CEIRR contracts have five main focus areas: longitudinal human influenza studies, influenza surveillance, risk assessment and response research, pre-pandemic and pandemic emergency response, and pathogenesis and immune response research. NIAID launched the first network of this kind in 2007, known then as Centers of Excellence for Influenza Research and Surveillance (CEIRS), awarding contracts every seven years for 14 years. “This contract will allow us to lead cutting-edge studies that have the potential to improve the seasonal flu vaccine that millions of people receive every year, and to be better prepared for the next flu pandemic.” “This is an opportunity for Penn Medicine to become a major hub for influenza research,” Dr. Scott Hensley, an associate professor of microbiology at the Perelman School of Medicine at the University of Pennsylvania, will serve as Penn’s CEIRR program director. The CEIRR contracts are a major funding mechanism for flu research in the Unites States. The contract is expected to be supported for six additional years. Penn Medicine has been awarded nearly $7 million in first-year funding.

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has selected Penn Medicine as one of five sites across the country to serve as a Center of Excellence for Influenza Research and Response (CEIRR), with the goals of better understanding influenza viruses around the world and learning about the viral strains that have the potential to cause pandemics. Penn Medicine: Nearly $7 Million to Study Influenza Viruses

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